You are viewing the site in preview mode
Skip to main content
|
Cancer Type
|
Treatment
|
Investigation
|
Results
|
Reference
|
|---|
|
LNCaP PC 3
|
Celecoxib
|
In vitro
|
Increased cell death/apoptosis
|
Kamijo 2001
|
|
PC 3
|
Celecoxib
|
In vitro/Xenograft
|
G1 block/reduced DNA synthesis/growth inhibition by COX-2 independent mechanism
|
Patel 1999
|
|
LNCaP PC 3
|
Celecoxib
|
In vitro
|
Growth inhibition
|
Srinath 2003
|
|
LNCaP PC 3
|
Celecoxib
|
In vitro
|
Induction of apoptosis by blocking Akt activation independently of Bcl-2
|
Hsu 2000
|
|
PC 3
|
Celecoxib+ radiation
|
In vitro
|
Up-regulation of COX-2, elevated PGE2 levels after irradiation
|
Steinauer 2000
|
|
LNCaP PC3 DU-145
|
Celecoxib+ radiation
|
In vitro
|
Bax-independent pro-apoptotic effect of Celecoxib
|
Handrick 2004
|
|
LNCaP DU-145 PC-3ML
|
Celecoxib+ COL-3/Docetaxel
|
In vitro/Xenograft
|
Augmentation of chemotherapeutic drug-induced apoptosis by activation of caspase 3 and 9
|
Dandekar 2005
|
