Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study

Table 4 Univariate and multivariate Cox regression analyses for factors affecting pain outcome

	Univariate Analyses			Multivariate Analysis
	HR	95% CI	p-value	HR	95% CI	p-value
Age	0.994	0.977–1.011	0.491
Gender	1.195	0.725–1.970	0.484
Volume	0.956	0.933–0.980	0.000
Integral dose	0.549	0.381–0.792	0.001	0.540	0.376–0.775	0.001
D_mean	1.027	0.987–1.068	0.189	1.041	1.002–1.080	0.038
Isodose	0.988	0.908–1.075	0.777
D_max	1.026	0.991–1.062	0.150
Prescription dose	1.578	0.984–1.020	0.209
Re-irradiation yes/no no as reference	0.732	0.315–1.699	0.467
Multiple sclerosis yes/no no as reference	0.340	0.162–0.714	0.004	0.332	0.156–1.002	0.004

ISSN: 1748-717X