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Table 2. Mean DVH metrics for HA-WBRT in current study compared to NRG CC001 constraints.

From: Automated contouring and planning pipeline for hippocampal-avoidant whole-brain radiotherapy

  NRG CC001  
Per protocol Acceptable variation Current study
Mean (range)
PTV D2% (Gy) < 37.5 37.5–40 34.3 (33.3–37.2)
PTV D98% (Gy) > 25 22.5–25 26.5 (25.3–28.8)
PTV V30Gy (%) > 95 90–95 95 (95–95)
Hippocampus D100% (Gy) < 9 9–10 8.1 (7.4–9.1)
Hippocampus Dmax (Gy) < 16 16–17 13.1 (9.7–15.7)
Optic Nerves Dmax (Gy) < 30 30–37.5 29.8 (25.4–32.3)
Optic Chiasm Dmax (Gy) < 30 30–37.5 30.1 (29.0–32.0)
  1. D dose, PTV planning target volume