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Characteristic
| |
V10 (%)
|
V20 (%)
|
V30 (%)
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V40 (%)
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V50 (%)
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V60 (%)
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V70 (%)
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|---|
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ORNJ
|
|
No
|
Median
|
92.90
|
86.59
|
76.61
|
65.07
|
41.68
|
12.16
|
0.03
|
|
Yes
|
Median
|
93.99
|
90.29
|
84.16
|
73.48
|
61.37
|
35.31
|
3.22
|
| |
p value*
|
0.4050
|
0.2340
|
0.0148
|
0.0016
|
< 0.0001
|
< 0.0001
|
0.0041
|
|
RT technique
|
|
3D-CRT
|
Median
|
87.57
|
81.37
|
76.07
|
70.47
|
52.84
|
26.62
|
0.21
|
|
IMRT
|
Median
|
99.42
|
92.92
|
79.39
|
53.95
|
27.30
|
5.33
|
0.00
|
| |
p value*
|
< 0.0001
|
< 0.0001
|
0.6300
|
< 0.0001
|
< 0.0001
|
< 0.0001
|
0.0001
|
|
Primary tumor site
|
|
OPC/OC
|
Median
|
95.04
|
90.24
|
83.21
|
73.87
|
56.26
|
32.03
|
0.00
|
|
Others
|
Median
|
88.99
|
82.00
|
69.43
|
57.59
|
32.86
|
3.98
|
1.19
|
| |
p value*
|
< 0.0001
|
< 0.0001
|
< 0.0001
|
< 0.0001
|
< 0.0001
|
< 0.0001
|
< 0.0001
|
- *Mann–Whitney U test
- V10, V20, V30, V40, V50, V60, and V70, represent relative volumes of the jaw exposed to 10, 20, 30, 40, 50, 60, and 70 Gy, respectively
- ORNJ, osteoradionecrosis of the jaw; RT, radiation therapy; 3D-CRT, 3-dimensional conformal radiation therapy; IMRT, intensity-modulated radiation therapy; OPC, oropharyngeal cancer; OC, oral cancer
