You are viewing the site in preview mode

Skip to main content

Table 5 Summary of the parameter values that have been reported by different groups for the LKB model, regarding the endpoint of xerostomia. The difference between the physician-scored (CTCAE) patient-reported (PRO-CTCAE) scoring systems is also indicated. Those model parameter sets were applied on the current dataset and the corresponding AUC, OR (with 95% confidence interval and dose threshold) values were calculated

From: NTCP modeling and dose–volume correlations for acute xerostomia and dry eye after whole brain radiation

Parameters D50 (Gy) m n AUC OR (95% CI)|thres
CTCAE  
Burman et al. [36] 46.0 0.18 0.7 0.53 0.0 (–)|–
Roesink et al. [37] 39.0 0.45 1.0 0.66 5.1 (1.1–23.4)|21
Braam et al. [38] 42.0 0.37 1.0 0.66 8.0 (1.8–35.6)|20
PRO-CTCAE  
Mavroidis et al. [35] 21.9 0.78 1.0 0.67 5.8 (1.5–23.2)|20
Back to article page

Radiation Oncology

ISSN: 1748-717X

Contact us

\